Of 7851 febrile participants, 134 (1.7%) had confirmed leptospirosis: 89 (1.1%) by ≥4-fold rise in Leptospira MAT titer between the acute and convalescent sample, 13 (0.2%) by a single Leptospira MAT reciprocal titer ≥800, and 38 (0.5%) by Leptospira lfb1 PCR. This evidence concerns the gene HNF1A and leptospirosis.