IFIH1 and asthma: This, in turn, may arise from activation of pattern recognition receptors (PRRs) such as TLR‐3 (Toll‐like Receptor 3), RIG‐I (retinoic acid inducible gene I) and MDA‐5 (melanoma differentiation‐associated protein 5) comparable to viral double‐stranded RNA [30], and parallel or affect antiviral innate immune responses (e.g., type I/III interferons) as it has been reported previously as possible mechanisms to contribute to asthma exacerbations.