Host defence mechanisms, including the epithelial release of the alarmin interleukin (IL) 25, chemokines, type I/III interferons and activation of the ER‐resident adaptor protein, stimulator of interferon genes (STING) or of the retinoic acid–inducible gene I (RIG‐I) inflammasome, have been reported to facilitate worsening asthma symptoms [6, 7, 8, 9]. The gene discussed is STING1; the disease is asthma.