The results showed that its co-expressed genes were significantly enriched in several critical biological processes, including “mitotic nuclear division,” “cell adhesion,” “ubiquitin-mediated proteolysis,” and the “Notch signaling pathway.” Based on these findings, we propose a hypothesis: SASH1 may exert its tumor-suppressive function by coordinately regulating multiple signaling pathways. The gene discussed is SASH1; the disease is neoplasm.