BCHE and neurodegenerative disease: Recently, hybrid molecules containing a phenothiazine fragment have been proposed as multifunctional agents for the potential treatment of neurodegenerative disease [128], cholinesterase modulators [129], acetylcholinesterase/butyrylcholinesterase inhibitors [130], antioxidants [131,132], and antitumor agents [133,134,135,136].