In binary analyses, replication revealed <i>POTEB3</i> rs2605913 (<i>p</i> = 2.8 × 10<sup>-8</sup>), while meta-analysis (<i>n</i> = 13,652) uncovered <i>SLC25A37</i> rs952825245 (<i>p</i> = 5.15 × 10<sup>-12</sup>), a locus associated with cancer and vitamin D signaling. This evidence concerns the gene POTEB3 and cancer.