CXCL1 and susceptibility to pneumonia measurement: To obtain an initial understanding of how SRT1720 affects the inflammatory response in the airways during Klebsiella-induced pneumonia, we measured cytokines (IL-6, TNF-α) and chemokines (CXCL1 and CXCL2) in BALF obtained 24 or 42 h after infection (Table 1).