TIMP2 and acute kidney injury: Patients with urinary [TIMP-2]·[IGFBP7] ≥0.5 ng ml−2 1000−1 after the RIPC intervention and before surgery had a significantly reduced rate of AKI compared with patients with a lower urinary [TIMP-2]·[IGFBP7] concentration, and the biomarker concentrations after surgery predicted subsequent development of AKI.9