Mutations in RYR1, the gene encoding RyR1, underlie several neuromuscular disorders, including malignant hyperthermia (MH; MIM #145600), central core disease (CCD; MIM #11700), specific forms of multi‐minicore disease and centronuclear myopathy (MmD, CNM; MIM # 255320) (Amburgey et al., 2013; Jungbluth et al., 2018; Lawal et al., 2020; Treves et al., 2017). This evidence concerns the gene RYR1 and Central core disease.