Our findings revealed that reduced expression of NEAT1 alleviated epileptic seizures, consistent with previous research indicating that NEAT1 can modulate seizure activity.[24] Specifically, NEAT1 influences seizure activity through regulating neuronal function and inflammatory responses.[22, 24] This hyperactivation is closely linked to the pathophysiology of TSC‐related epilepsy. Here, NEAT1 is linked to epilepsy.