The therapeutic mechanism of Yimusake involves improving endothelial function and increasing testosterone levels by modulating the gonadal axis, activating nitric oxide/guanosine cyclic phosphate and vasoactive intestinal peptide/adenosine cyclic phosphate, etc.15Does Yimusake inhibit oxidative stress, improve endothelial dysfunction and promote erectile tissue recovery in DMED rats by down-regulating the NLRP3 inflammasome-mediated NF-κB signaling pathway? The gene discussed is NFKB1; the disease is endothelial dysfunction.