Pituitary removal combined with HFD induced significant hyperlipidemia, characterized by elevated serum TC, TG, and LDL‐C, as well as reduced serum HDL‐C and IGF‐1 in C57‐Hx mice (Figures 1d, 1e, 1f, 1g, and 1h). Here, IGF1 is linked to hyperlipidemia.