Similarly, TIM-3 in the tumor microenvironment was also an independent factor that affected the clinical outcome of EOC patients (PFS: HR = 1.99, 95% CI = 1.29-3.08, P = .002; OS: HR = 2.13, 95% CI = 1.37-.30, P = .001). Here, HAVCR2 is linked to neoplasm.