Among the top 10 genes conferring a substantial risk for schizophrenia, the SCHEMA consortium revealed two components of different glutamate receptors, i.e. GRIN2A encoding the GluN2A subunit of the NMDAR as well as GRIA3 encoding the GluR3 subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR). This evidence concerns the gene GRIA3 and schizophrenia.