DTNBP1 and cyst: Interestingly, loss of function pallidin (BLOC1S6) and dysbindin (BLOC1S8) in Dtnbp1sdy/sdy and Pldnpa/pa mice, respectively, gave rise to significant dilations in collecting duct and proximal tubules of the kidney (89), which is consistent with our finding of increased cystogenesis in an in vitro cyst model.