GPT and infection: ,30 In a first experiment, we compared 2 × 106 FFU LCMV-WE with 2 × 106 FFU WE-CL13-GP181M-185W-492I, which resulted in fast weight loss and high levels of serum alanine transaminase (ALT), aspartate transaminase (AST), and lactate dehydrogenase (LDH) in FVB mice after infection with LCMV-WE, while mice infected with WE-CL13-GP181M-185W-492I showed substantially limited effects (Figures S6A and S6B).