The intersection obtained in A-673 was validated in a second Ewing sarcoma cell line, TC-71, in which we found 1,163 common peaks between EWSR1::FLI1 and KDM6A/KDM6B (P value < 0.05; FDR <10−5 in all cases; Supplementary Fig. S2D). Here, KDM6B is linked to Ewing sarcoma.