This disruption interferes with the PKA‐dependent interaction between cell division cycle 37 (CDC37) and heat shock protein 90 (HSP90), leading to improper folding and subsequent degradation of AXL.[127] Additionally, NSAIDs suppress nuclear factor‐kappa B (NF‐κB), a well‐known anti‐apoptotic transcription factor implicated in melanoma progression.[128]. The gene discussed is NFKB1; the disease is melanoma.