To address vascular dysfunction following ischemic stroke in ITGA8‐deficient mice, we investigated therapeutic ITGA8 restoration using an adeno‐associated virus vector (AAV‐PR) targeting mural cells,[34] with pericyte‐specific transduction confirmed in Pdgfrb‐Cre; H11‐tdTomato‐GFP reporter mice (Figure S10A, Supporting Information). Here, ITGA8 is linked to ischemic stroke.