Von Willebrand disease (VWD) is a common inherited bleeding disorder caused by quantitative (Type 1 and Type 3) or qualitative (Type 2) defects in von Willebrand factor (VWF), which stabilises Factor VIII (FVIII) and supports platelet adhesion [1, 2, 3]. This evidence concerns the gene VWF and von Willebrand disease (hereditary or acquired).