From our population considered as PUPs (18 including three Type 3 VWD), one can see that no allergic reactions or anti‐VWF antibodies were observed, as was the case in Gouider et al., where the three PUPs (all Type 3 VWD) were followed for at least 18 months [10]. Here, VWF is linked to von Willebrand disease (hereditary or acquired).