For example, PSAP can interact with other receptors, such as the low‐density lipoprotein receptor‐related protein (LRP), which may also play roles in IDD.[70, 71, 72, 73] Future work should aim to comprehensively map the signaling networks regulated by PSAP in IDD to identify additional therapeutic targets. The gene discussed is PSAP; the disease is intervertebral disk degenerative disorder.