This research not only represented a pioneering endeavor to unravel the collective and synergistic role of these entities in the fibrosis progression of peritoneal adhesion but also pioneered the identification of FOXC2 as a linchpin through its synergistic effects between the TGF‐β1‐Smad2/3 signaling axis and NETs formation to subsequent EMT alteration during PPA pathogenesis. The gene discussed is SMAD2; the disease is primary progressive aphasia.