For instance, pathways related to IL‐4 and IL‐13 signaling (IL4R, FOS, CEBPD, JUNB), which reinvigorate terminally exhausted intratumoral CD8+ T cells,[37] and those involved in regulated necrosis and interferon signaling (IFNG, GZMB, CASP4, IRF8, ISG20, IFITM1, IFITM3, GBP5), crucial for tumor restriction, were enriched in tumoral NK cells. Here, IFITM3 is linked to neoplasm.