The upregulation of oxidative stress‐related genes, such as PTGS2, and the downregulation of GPX4 are considered classic hallmarks of ferroptosis.[20, 21] Moreover, the degradation of ferritin heavy chain (FTH) contributes to Fe2+ accumulation, which can be modulated through STING‐mediated autophagy.[22, 23, 24] Ferroptosis has been closely linked to various diseases, including cancer, inflammation, and metabolic disorders.[20, 21] Recent studies have demonstrated that increased ferroptosis plays a role in the pathogenesis of PCOS. The gene discussed is STING1; the disease is polycystic ovary syndrome.