TWIST1 and breast cancer: reported that circGSK3β facilitates PD‐L1 transcription and immune evasion in BC via the miR‐338‐3p/PRMT5/H3K4me3 axis.[35] In our study, circLRBA could competitively bind to the E3 ubiquitin ligase SPOP to inhibit the interaction between SPOP and Twist1 and the degradation of Twist1.