Moreover, it has been demonstrated that hUC‐MSCs alleviate neuropathological changes in Alzheimer's disease (AD) models by secreting hepatocyte growth factor (HGF), enhancing synaptic plasticity, and promoting endogenous neurogenesis (Cao et al. 2017; Jia et al. 2020). The gene discussed is HGF; the disease is early-onset autosomal dominant Alzheimer disease.