Recent advances in genetics have revealed RSRC1 mutations are associated with aberrant human brain development: RSRC1 polymorphism is associated with schizophrenia (Potkin et al. 2009), and patients homozygous for loss‐of‐function RSRC1 mutations exhibit developmental delay and intellectual disability (Perez et al. 2018; Scala et al. 2020). This evidence concerns the gene RSRC1 and Global developmental delay.