To verify whether Kcne1 overexpression could rescue the increased susceptibility to AF that may be resulting from Fto overexpression, 2‐month‐old male mice were intravenously injected with AAV9‐cTnT‐Fto‐oe, with or without AAV9‐cTnT‐Kcne1‐oe. The gene discussed is KCNE1; the disease is atrial fibrillation.