CKM and atrial fibrillation: We evaluated CKM domains and their impact in a real-world cohort of patients with AF.<h4>Methods</h4>From the prospective global GLORIA-AF Registry phase III study, we defined CKM domains according to cardiovascular, renal and metabolic comorbidities or conditions in patients with AF and CHA<sub>2</sub>DS<sub>2</sub>-VASc score ≥ 1.