After clumping, we identified 18 regions (2 mapping to ARHGEF18 (19p13.2) and ARHGEF19 (1p36.13) were novel) which showed the smallest p-values in the cleft lip with or without cleft palate (CL/P) or nsCL/P subtype GWAS and which were associated with both CLO and CLP. The gene discussed is ARHGEF19; the disease is cleft palate.