According to the United Kingdom (UK) National Haemophilia Database, it was estimated that 16.5 per 100 000 people in the UK had VWD (all types) in 2020 (type 1: 7.2 per 100 000 people; type 2: 2.5 per 100 000; type 3: 0.3 per 100 000; remaining patients ‘unclassified’ or ‘low von Willebrand factor’ [VWF]) [2]. Here, VWF is linked to hemophilia.