While less commonly studied in ALS, spinal interneurons do exhibit neurodegeneration and cell loss in a similar manner to motor neurons in ALS patient postmortem samples (Stephens et al. 2006) and TDP‐43 related mouse models of ALS (Reale et al. 2023; Tsuboguchi et al. 2023). This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.