Significantly, prior research has demonstrated the crucial function of the NRF2/KEAP1 signaling pathway in carcinogenesis and the relationship between redox and metabolism in cancer (Hayes and Dinkova-Kostova 2014), providing additional evidence that Nrf2 acts as an oncogene to encourage tumor cell motility and invasion, potentially by boosting the tumor’s resistance to oxidative stress. Here, KEAP1 is linked to cancer.