CXCL8 and coronary artery disorder: In addition to the IL-8 gene, there were several other DE genes in our analysis that contribute to inflammation, as evident from the results of pathway analysis, which shows the enrichment of several pathways, including “chemokine signaling pathway,” “CCKR signaling,” and “Toll-like receptors cascades.” All these pathways are part of the inflammatory bandwagon in CAD (9, 34, 35).