For example, we estimated that 72.6% [95% CI = (49.2%, 96.1%)] of the effect of FGF5 on CAD may be mediated through SBP (see Supplementary data online, Table S26; Figure 4), and 77.2% [95% CI = (31.9%, 100%)] of the effect of FGF5 on AIS mediated through SBP. This evidence concerns the gene FGF5 and coronary artery disorder.