Of these, 5 proteins (ACOX1, BRAP, ERP29, FGF5, and FURIN) also showed strong colocalization with CAD and/or stroke and all had concordant direction of effects for BP and CAD and/or stroke (see Supplementary data online, Figures S12 and S13; Supplementary data online, Table S20). This evidence concerns the gene FGF5 and stroke disorder.