So far, variants in more than 50 different genes have been associated with PCD, affecting many structural elements of the axoneme (Legendre et al., 2021), with variants in the ODA heavy chain gene DNAH5 being responsible for at least a third of north European PCD cases (Fassad et al., 2020; Hornef et al., 2006). Here, DNAH5 is linked to primary ciliary dyskinesia.