INPP1 and polycystic kidney disease 2: Although there was no difference in PKD-2 ciliary localization in the inpp-1 mutant right after mounting the animals for imaging, after 40 min, we found that PKD-2 was absent from the cilium proper and distal tip in 28% of the inpp-1 mutant RnB cilia examined, a significantly higher percentage than observed for wild type (Fig. 6A,B).