This potentially disrupts the fusionof phagosomes and lysosomes, a process dependent on actin polymerization.Moreover, our observation here of differential and unique phosphorylationof other GEFs and/or actin-binding proteins, including DENND4C, ARFGEF2,and DOCK10, further supports the hypothesis that PknG contributesto the blockade of phagosome-lysosome fusion by directly or indirectlymodulating actin dynamics during infection. This evidence concerns the gene DOCK10 and infection.