Myoferlin is recognized as an emerging oncoprotein (Gupta et al, 2021; Blomme et al, 2017; Rademaker et al, 2019), highlighted by the overexpression of myoferlin in several cancer types, including PAAD with the highest expression and the greatest overexpression compared to healthy pancreas (Fig. EV1A). The gene discussed is MYOF; the disease is cancer.