Friedman et al. [9] examined Whole Exome Sequences (WES) derived from brain samples in eight epileptic patients deceased from SUDEP and identified variants in cardiac arrhythmia-associated genes (KCNMB1, KCNIP1, DPP6, JUP, F2, and TUBA3D) that were not present in living epileptic controls. Here, JUP is linked to chronic obstructive pulmonary disease.