This finding is of interest, since previous studies showed that systemic BMP10 levels are related to cardiovascular events and recurrent AF.8,9,20–22 Overall, in this exploratory analysis, ANGPT2, in contrast to BMP10, may therefore be useful to estimate atrial cardiomyopathy severity in addition to NT-proBNP. This evidence concerns the gene NPPB and atrial fibrillation.