IL4 and atopic eczema: The elevated levels of IL‐4 in the microenvironment of skin lesions play a pivotal role in the pathogenesis of atopic dermatitis.[18, 19] Stimulation of primary mouse skin fibroblasts with IL‐4 to induce their transformation into inflammatory fibroblasts resulted in a significant elevation in the expression of genes related to the MIF pathway (Figure S1, Supporting Information).