This study aims to evaluate the association between three ADIPOQ gene variants-rs266729, rs2241766, and rs1501299-and the risk of AMI in Vietnamese patients with T2DM.<h4>Methods</h4>A case-control study was conducted from January 2023 to June 2024 at the University Medical Center, Ho Chi Minh City. The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.