VEGFA and hereditary clear cell renal cell carcinoma: Renal cell carcinoma (RCC) is among the most common malignancies of the genitourinary system, with clear cell RCC (ccRCC) accounting for over 80% of cases.[1, 2] A hallmark of ccRCC is its highly vascular nature, largely driven by dysregulated hypoxia‐inducible factor (HIF) signaling and overexpression of vascular endothelial growth factor (VEGF).