MYH11 and acute myeloid leukemia: WGS analysis for structural variants suggested 106 AML-associated oncogenic or likely oncogenic fusions in 105 cases (SJ031259 harbored both CBFB::MYH11 and a CNTRL::KIT fusion), of which 96 were predicted to produce fusion oncogenes (in-frame exon-exon junction fusions) and 10 were suspected to be enhancer-hijacking structural alterations that activate adjacent oncogenes (Fig. 2).