In EATL, where available data is limited, the potential implication of SETD2 is controversial, and overlap in mutational portrait has been reported with both MEITL and type II refractory CeD, notably in JAK1 (at the p.G1097 hotspot) and STAT3 [13, 14, 19]. The gene discussed is STAT3; the disease is enteropathy-associated T-cell lymphoma.