However, among the most compelling findings are unknown ancestry- or tumour-associated African-specific PCa target genes, which include functionality ranging from developmental signalling (EVC2, CHSY1), cell cycle regulation (SPDYA), ion homeostasis (SLC12A9), glucose metabolism (GALM), to inflammatory response and apoptosis (PYCARD). The gene discussed is SPDYA; the disease is posterior cortical atrophy.