For example, dysregulated expression of DNA methyltransferases (DNMT) [DNA methyltransferase 1 (DNMT1), DNA methyltransferase 3A (DNMT3A), and DNA methyltransferase 3B (DNMT3B)] in endometriotic lesions, along with differential DNA methylation patterns in genes involved in inflammatory pathways, steroid signaling, and apoptosis, have been linked to the progression of endometriosis (17, 18). This evidence concerns the gene DNMT3A and endometriosis.