DNMT1 and endometriosis: For example, dysregulated expression of DNA methyltransferases (DNMT) [DNA methyltransferase 1 (DNMT1), DNA methyltransferase 3A (DNMT3A), and DNA methyltransferase 3B (DNMT3B)] in endometriotic lesions, along with differential DNA methylation patterns in genes involved in inflammatory pathways, steroid signaling, and apoptosis, have been linked to the progression of endometriosis (17, 18).