PRKN and glycogen storage disease VI: Compared with control luci worms, oxygen consumption assays in epg‐5‐deficient C. elegans showed an increase in the differential between maximum and basal oxygen consumption rate (“spare capacity”), indicative of an excess of uncoupled capacity of the respiratory electron transport chain, similar to observations with knockdown of other autophagosome–lysosome fusion (ccz‐1/CCZ1) and Parkinson's disease‐associated genes (pdr‐1/PRKN) in worms (Fig 7C).