Other notable additional features included thalamic involvement (n = 15), the “ear of the lynx sign” (a fluid‐attenuated inversion recovery cone shaped periventricular hyperintensity usually associated with SPG11‐ and SPG15‐spastic paraplegia; n = 3), iron accumulation in the basal ganglia (n = 5), and copper accumulation in the midbrain (n = 1; Fig 3N,O, Fig 3Q). The gene discussed is ZFYVE26; the disease is Spastic paraplegia.