Consistent with these findings, immunohistochemistry analysis on tissue microarrays of tumor and adjacent normal tissues further demonstrated that TPRA1 expression is selectively upregulated in 76% of lung adenocarcinoma, 55% of bladder urothelial carcinoma, and 53% of prostate adenocarcinoma cases compared to their corresponding normal tissue (Figure 6E,F). This evidence concerns the gene TPRA1 and lung adenocarcinoma.