Furthermore, a meta-analysis study of the prognostic role of LAG-3 expression in cancer patients (breast, ovarian, gastric, lymphoma, non-small cell lung cancer, colorectal, renal cancers and pediatric neuroblastoma) showed an association of LAG-3 expression with a better overall survival in early-stage solid tumors [34]. This evidence concerns the gene LAG3 and non-small cell lung carcinoma.